Are Omicron BA.4 and BA.5 from a Lab?
And maybe the Original Omicron found in Botswana
We know Tedros believes the original Sars-Cov-2 virus has lab origin
https://www.nspirement.com/2022/07/15/who-tedros-adhanom-ghebreyesus.html
What about the Variants?
Omicron was first detected by Botswana, in four foreign nationals who were Diplomats and had recently entered the country.
https://www.visiontimes.com/2021/11/26/botswana-vaccinated-diplomats.html
So now were are on Omicron BA 4-5, which some call Deltacron. The early variant of Omicron brought to Botswana was so different from Delta some suspected GOF Lab Release. After all who were those Foreign Diplomats who were the first cases detected in Botswana that nobody seems to care about. The silence is deafening.
Fortunately, infectious as it was Omicron was only 10% as deadly as Delta. Some of us saw it as a self spreading vaccine which would have far fewer Adverse Events than Big Phamas concoctions
Now it seems some are suggesting the new Omicron Variants are taking the worst from Delta and Early Omicron and will be a big problem. I am not so convinced of this since surely so many have been exposed to Sars-Cov-2 by now we must have some semblance of herd immunity.
Of course, we probably do among the unvaccinated. However, those dependent on vaccine generated antibodies with a suppressed and dysregulated immune system might not be so lucky
Great post here describing how a Chinese Lab did GOF to on Omicron to create Deltacron at the same time something similar gets detected in South Africa? Fauci had nothing to do with this one
Here is the paper he referenced
SARS-CoV-2 spike L452R mutation increases Omicron variant fusogenicity and infectivity as well as host glycolysis
Received10 February 2022
Published09 March 2022
[This work must have been started in Dec/Jan. Original Omicron was first announced November 25,2021]
Acknowledgements
This work was supported by the National Key Research and Development Program of China (2017YFA0505602), the National Natural Science Foundation (81930078, 81872246, 81802756, 31470773 and 81773135) and Military Medical Innovation Project (18CXZ047).
Author information
Author notes
These authors contributed equally: Yanan Zhang, Ting Zhang, Yihui Fang.
The L452R mutation, one of the most frequent mutations , is the only RBD domain mutation that emerges in the Delta variant but is absent in the Omicron variant. It has been reported that L452R mutation increases SARS-CoV-2 fusogenicity and infectivity. Here, we developed an L452R mutated Omicron variant (Omicron-L452R) and found that the Omicron-L452R variant rescued fusogenicity and strengthened the high infectivity by enhancing the cleavage of the spike protein. Notably, Omicron-L452R greatly enhanced the ability of Omicron to infect lung tissues of humanized ACE2 mice. Furthermore, the Omicron-L452R variant dramatically enhanced glycolysis in host cells. Our data suggest that the decreased fusogenicity of the Omicron variant is due to a lack of the L452R mutation present in the Delta variant.
https://www.nature.com/articles/s41392-022-00941-z
BA.4 and BA.5 were first detected in South Africa in January and February 2022, respectively, and since then they have become the dominant variants there. Both lineages contain the amino-acid substitutions L452R, F486V, and R493Q in the spike receptor binding domain compared to BA.2. Preliminary studies suggest a significant change in antigenic properties of BA.4 and BA.5 compared to BA.1 and BA.2, especially compared to BA.1. Additionally, there is an increasing trend in the variant proportions for BA.5 observed in Portugal the recent weeks, accompanied by an increase in COVID-19 case numbers and test positivity rate.
I am getting a strong feeling some of these variants may not be naturally occurring
And of course, Pfizer is now working on a Booster which will include both Wuhan virus mRNA (why) and Deltacron (BA.4, BA.5)
We even got Rand Paul shilling for a new vaccine to handle Deltacron
"How come the flu vaccine changes every year and they're not willing to change this vaccine?" he said. "Now, you might have me with an argument. I'll listen to you if you tell me, 'We've got a new vaccine that actually has something to do with the current virus,'" he said.
https://www.msn.com/en-us/news/politics/latest-covid-variant-sensationalized-by-white-house-rand-paul/ar-AAZvxTM
Surely Paul cant be ignorant of the fact that FDA and Pfizer are working on that
The US Food and Drug Administration made a recommendation last week that vaccine manufacturers should make a booster dose of COVID-19 vaccine that targets the omicron variant -- specifically, BA.4 and BA.5 subvariants
https://www.cnet.com/health/medical/new-covid-vaccine-for-fall-what-to-know-about-the-fdas-plans/